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Prostate Cancer treatment details. Biologic therapy. Chemotherapy. Wayne State University, Detroit,MI, United States



Survival: 11.2 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
Chemotherapy
   
Drugs:
Country: United States
   
City/State/Province: Detroit,MI
   
Hospital: Wayne State University
   
Journal: Link
   
Date: 2/2013

Description:
Patients:
This phase 2 study involved 31 metastatic castrate-resistant prostate cancer patients who had been previously treated with docetaxel. The median patient age was 67 years.

Treatment:
Patients were treated with the biologic therapy agent bevacizumab and the chemotherapy agent satraplatin.

Toxicities:
The most severe toxicities were of grade 4 and included blood clots and thrombocytopenia. Grade 3 diarrhea and dehydration were also reported.

Results:
The median overall survival was 11.2 months.

Support:
This study was supported by Genentech Inc. and GPC Biotech.

Correspondence: Dr. Ulka N.Vaishampayan; email: vaishamu@karmanos.org

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