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Breast Cancer treatment details. Biologic therapy. The Sarah Cannon Research Institute and Tennessee Oncology, Nashville, TN, United States

Survival: 15.6 months
Toxicity Grade: 5
Treatments: Biologic therapy
Country: United States
City/State/Province: Nashville, TN
Hospital: The Sarah Cannon Research Institute and Tennessee Oncology
Journal: Link
Date: 12/2012

This phase 2 study involved 83 women with metastatic or advanced breast cancer. The median patient age was 58 years.

Patients were treated with the biologic therapy agent sunitinib, a tyrosine kinase inhibitor that interferes with blood supply to the tumor.

There were two treatment-related deaths due to pulmonary embolism and heart attack. Grade 3-4 fatigue, neutropenia, and thrombocytopenia were also reported.

The median overall survival was 15.6 months.

This study was supported by Pfizer, Inc.

Correspondence: Dr. Denise A. Yardley; email:

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