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Bladder Cancer treatment details. Chemotherapy. Athens University Medical School, Athens, Greece

Survival: 19.0 months
Toxicity Grade: 5
Treatments: Chemotherapy
Drugs: Adriamycin
Country: Greece
City/State/Province: Athens
Hospital: Athens University Medical School
Journal: Link
Date: 4/2013

This phase 3 study involved advanced urothelial cancer patients who were divided into two separate treatment groups. Group A consisted of 63 patients with a median age of 66 years and 84.1% male. Group B had 63 patients with a median age of 65 years and 87.3% male.

Patients in group A were treated with the chemotherapy agents methotrexate, vinblastine, adriamycin, and cisplatin.

Patients in group B were treated with the chemotherapy agents gemcitabine and cisplatin.

There were two treatment-related deaths in group A due to infection. Grade 4 neutropenia and grade 3 fatigue were also reported.

The most severe toxicities in group B were of grade 4 and included anemia and neutropenia. Grade 3 infection and fatigue were also reported.

The median overall survival for groups A and B was 19 and 18 months, respectively.

Correspondence: Dr. A. Bamias; email:

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