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Colon Cancer treatment details. Biologic therapy. Chemotherapy. Vejle Hospital, Vejle, Denmark



Survival: 5.3 months
   
Toxicity Grade: 3
   
Treatments: Biologic therapy
Chemotherapy
   
Drugs:
Country: Denmark
   
City/State/Province: Vejle
   
Hospital: Vejle Hospital
   
Journal: Link
   
Date: 6/2013

Description:
Patients:
This phase 2 study involved 64 previously treated patients with KRAS-mutant metastatic colorectal cancer. The median patient age was 62 years and 56% were male.

Treatment:
Patients were treated with the biologic therapy agent temsirolimus (an inhibitor of the mTOR protein that interferes with cancer cell growth) and the chemotherapy agent irinotecan.

Toxicities:
The most severe toxicities were of grade 3 and included infection, fever, and high blood sugar.

Results:
The median overall survival was 5.3 months.

Correspondence: Dr. Karen-Lise G. Spindler; email: Karen-Lise.Garm.Spindler@slb.regionsyddanmark.dk

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