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Melanoma treatment details. Biologic therapy. Chemotherapy. University of Washington, Seattle, WA, United States



Survival: 11.0 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
Chemotherapy
   
Drugs:
Country: United States
   
City/State/Province: Seattle, WA
   
Hospital: University of Washington
   
Journal: Link
   
Date: 11/2012

Description:
Patients:
This phase 2 study involved 24 metastatic uveal melanoma patients. The median patient age was 61 years and 50% were male.

Treatment:
Patients were treated with the chemotherapy agents carboplatin and paclitaxel, as well as the biologic therapy agent sorafenib.

Toxicities:
The most severe toxicities were of grade 4 and included neutropenia and leukopenia. Grade 3 nerve toxicity, rash, and diarrhea were also reported.

Results:
The median overall survival was 11 months.

Correspondence: Dr. Shailender Bhatia; email: sbhatia@uw.edu

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