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Non-Hodgkin's Lymphoma treatment details. Biologic therapy. Stanford University, Stanford, CA, United States



Survival: 9.0 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
   
Drugs:
Country: United States
   
City/State/Province: Stanford, CA
   
Hospital: Stanford University
   
Journal: Link
   
Date: 7/2013

Description:
Patients:
This phase 2 study involved 14 recurrent diffuse large B cell lymphoma patients who had been previously treated. The median patient age was 69.5 years and 9 were male.

Treatment:
Patients were treated with the biologic therapy agent sorafenib, which is a protein kinase inhibitor that is involved in the growth of cancer cells.

Toxicities:
The most severe toxicities were of grade 4 and included fatigue and low platelet count. Grade 3 rash and diarrhea were also reported.

Results:
The median overall survival was 9 months.

Support:
One of the authors of the study is employed by the Roche-Genentech pharmaceutical company.

Correspondence: Dr. Daniel R Greenwald; email: dgreenwald@ccsb.org

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