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Colon Cancer treatment details. Chemotherapy. University of Oxford, Oxford, United Kingdom

Survival: 14.8 months
Toxicity Grade: 4
Treatments: Chemotherapy
Drugs: Adrucil
Country: United Kingdom
City/State/Province: Oxford
Hospital: University of Oxford
Journal: Link
Date: 2/2003

Patients: 290 patients with colorectal cancer with metastases confined to the liver were involved in this study. Patients were divided into two groups: an intrahepatic treatment group composed of 145 patients and an intravenous group composed of 145 patients.

Treatment: For the intravenous group the treatment consisted of the administration of intravenous fluorouracil (adrucil) and folinic acid (leucovorin).

Toxicity: Grade 3 or 4 toxicities were rare and included: neutropenia, nausea, vomiting, anorexia, skin rashes, stomatitis, and diarrhea.

Results: Median overall survival was 14.8 months.

Correspondence: Prof. David J. Kerr

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