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Colon Cancer treatment details. Biologic therapy. Chemotherapy. Nihon University School of Medicine, Tokyo, Japan

Survival: 22.0 months
Toxicity Grade: 4
Treatments: Biologic therapy
Drugs: Leucovorin
Country: Japan
City/State/Province: Tokyo
Hospital: Nihon University School of Medicine
Journal: Link
Date: 9/2013

This phase 2 study involved 39 metastatic colorectal cancer patients. The median patient age was 65 years and 61.5% were male.

Patients were treated with the chemotherapy combination called FOLFIRI (irinotecan, 5-fluorouracil, and leucovorin) plus the biologic therapy agent bevacizumab.

The most severe toxicities were of grade 4 and included neutropenia and anemia. Grade 3 stomatitis (inflammation of stomach lining) and anorexia were also reported.

The median overall survival was 22 months.

Correspondence: Dr. Mitsugu Kochi; email: kochi.mitsugu@nihon‑

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