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Colon Cancer treatment details. Biologic therapy. Chemotherapy. National Hospital Organization Shikoku Cancer Center, Matsuyama, Japan



Survival: 28.5 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
Chemotherapy
   
Drugs:
Country: Japan
   
City/State/Province: Matsuyama
   
Hospital: National Hospital Organization Shikoku Cancer Center
   
Journal: Link
   
Date: 9/2013

Description:
Patients:
This study involved 68 advanced/recurrent colorectal cancer patients who had not received prior chemotherapy. The median patient age was 63 years and 38 were male.

Treatment:
Patients were treated with the chemotherapy agents 5-fluorouracil, levofolinate calcium, and oxaliplatin, in addition to the biologic therapy agent bevacizumab.

Toxicities:
The most severe toxicities were of grade 4 and included neutropenia, peripheral neuropathy (nerve toxicity), and hypertension.

Results:
The median overall survival was 28.5 months.

Support:
This study was sponsored by the pharmaceutical company Yakult Honsha Co., Ltd.

Correspondence: Dr. Tomohiro Nishina; email: tnishina@shikoku-cc.go.jp

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