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Liver Cancer treatment details. Chemotherapy. Ain Shams University, Cairo, Egypt



Survival: 5.0 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs:
Country: Egypt
   
City/State/Province: Cairo
   
Hospital: Ain Shams University
   
Journal: Link
   
Date: 9/2013

Description:
Patients:
This involved advanced hepatocellular carcinoma patients who were divided into two separate treatment groups. Group A had 26 patients with a median age of 53.5 years. Group B had 26 patients with a median age of 59.5 years. Gender information was not provided.

Treatment:
Patients in group A were treated with the biologic therapy agent sorafenib.

Patients in group B were given chemotherapy with cisplatin.

Toxicities:
The most severe toxicities in group A were of grade 4 and included hand–foot skin reaction, fatigue, and liver dysfunction.

In group B, the most severe toxicities were of grade 4 and included grade 3-4 liver dysfunction and thrombocytopenia.

Results:
The median overall survival was 7.05 months in group A and 5.07 months in group B.

Correspondence: Dr. Omar Abdel-Rahman; email: omar.abdelrhman@med.asu.edu.eg

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