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Prostate Cancer treatment details. Biologic therapy. Advocate Lutheran General Hospital, Park Ridge, IL, United States



Survival: 13.0 months
   
Toxicity Grade: 5
   
Treatments: Biologic therapy
   
Drugs:
Country: United States
   
City/State/Province: Park Ridge, IL
   
Hospital: Advocate Lutheran General Hospital
   
Journal: Link
   
Date: 10/2013

Description:
Patients:
This phase 2 study involved 21 castration-resistant prostate cancer patients who had not received prior chemotherapy. The median patient age was 74 years.

Treatment:
Patients were treated with the biologic therapy agent temsirolimus, which is an inhibitor of the mTOR protein that interferes with cancer cell growth.

Toxicities:
Death due to intracerebral bleeding and surgical complications were reported for this study, but were considered not related to treatment. Grade 3-4 fatigue, pain and pneumonia were also reported.

Results:
The median overall survival was 13 months.

Correspondence: Dr. C Nabhan; email: cnabhan@medicine.bsd.uchicago.edu

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