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Prostate Cancer treatment details. Biologic therapy. Advocate Lutheran General Hospital, Park Ridge, IL, United States

Survival: 13.0 months
Toxicity Grade: 5
Treatments: Biologic therapy
Country: United States
City/State/Province: Park Ridge, IL
Hospital: Advocate Lutheran General Hospital
Journal: Link
Date: 10/2013

This phase 2 study involved 21 castration-resistant prostate cancer patients who had not received prior chemotherapy. The median patient age was 74 years.

Patients were treated with the biologic therapy agent temsirolimus, which is an inhibitor of the mTOR protein that interferes with cancer cell growth.

Death due to intracerebral bleeding and surgical complications were reported for this study, but were considered not related to treatment. Grade 3-4 fatigue, pain and pneumonia were also reported.

The median overall survival was 13 months.

Correspondence: Dr. C Nabhan; email:

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