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Bladder Cancer treatment details. Biologic therapy. Memorial Sloan-Kettering Cancer Center, New York, NY, United States



Survival: 8.3 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
   
Drugs:
Country: United States
   
City/State/Province: New York, NY
   
Hospital: Memorial Sloan-Kettering Cancer Center
   
Journal: Link
   
Date: 4/2013

Description:
Patients:
This phase 2 study involved 45 advanced urothelial carcinoma patients. The median patient age was 66 years and 69% were male.

Treatment:
Patients were treated with the biologic therapy agent everolimus, which is an mTOR inhibitor that interferes with cancer cell growth.

Toxicities:
The most severe toxicities were of grade 4 and included grade 3-4 fatigue, lung inflammation, and infection.

Results:
The median overall survival was 8.3 months.

Support:
This study was partially supported by Novartis Pharmaceuticals Corporation.

Correspondence: Dr. Matthew I. Milowsky; email: matt_milowsky@med.unc.edu

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