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Breast Cancer treatment details. Biologic therapy. Chemotherapy. The Ohio State University Comprehensive Cancer Center, Columbus, OH, United States



Survival: 11.2 months
   
Toxicity Grade: 5
   
Treatments: Biologic therapy
Chemotherapy
   
Drugs:
Country: United States
   
City/State/Province: Columbus, OH
   
Hospital: The Ohio State University Comprehensive Cancer Center
   
Journal: Link
   
Date: 7/2012

Description:
Patients:
This phase 2 study involved 22 metastatic breast cancer patients who had received prior taxane-based chemotherapy. The median patient age was 56 years.

Treatment:
Patients were treated with the chemotherapy agent paclitaxel and the biologic therapy agent called suramin, which is a growth factor inhibitor.

Toxicities:
There was one death attributed to progressive disease and Acute Respiratory Distress Syndrome. Grade 4 leukopenia, neutropenia, and shortness of breath were also reported.

Results:
The median overall survival was 11.2 months.

Correspondence: Dr. Maryam B. Lustberg; email: maryam.lustberg@osumc.edu

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