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Breast Cancer treatment details. Biologic therapy. Chemotherapy. Kyoto University, Kyoto, Japan



Survival: 19.0 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
Chemotherapy
   
Drugs:
Country: Japan
   
City/State/Province: Kyoto
   
Hospital: Kyoto University
   
Journal: Link
   
Date: 3/2012

Description:
Patients:
This phase 2 study involved 19 female metastatic breast cancer patients who had received prior anthracycline-based chemotherapy. The median patient age was 54 years.

Treatment:
Patients were treated with the chemotherapy agent docetaxel and the biologic therapy agent called TSU-68, which is a multiple tyrosine kinase inhibitor that interferes with cancer cell growth.

Toxicities:
The most severe toxicities were of grade 4 and included neutropenia and leukopenia. Grade 2 alopecia was reported by 63.2% of patients.

Results:
The median overall survival was 19 months.

Correspondence: Dr. Masakazu Toi; email: toi@kuhp.kyoto-u.ac.jp

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