Cancer Treatment Results  Survival Rates Cancer Treatments / Therapy Results
Cancer
 

Click here to go back to your search results.

Prostate Cancer treatment details. Biologic therapy. Duke University Medical Center, Durham, NC, United States



Survival: 8.8 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
   
Drugs:
Country: United States
   
City/State/Province: Durham, NC
   
Hospital: Duke University Medical Center
   
Journal: Link
   
Date: 12/2013

Description:
Patients:
This phase 2 study involved 11 previously treated, castration-resistant, metastatic prostate cancer patients. The median patient age was 61 years.

Treatment:
Patients were treated with the biologic therapy agent called temsirolimus, an mTOR protein inhibitor that interferes with cancer cell growth.

Toxicities:
The most severe toxicities were grade 4 hypophosphatemia (electrolyte imbalance) and brain hemorrhage. Grade 3 fatigue and muscle weakness were also reported.

Results:
The median overall survival was 8.8 months.

Support:
This study was partially funded by Pfizer.

Correspondence: Dr. Andrew J Armstrong; email: andrew.armstrong@duke.edu

E-mail to a Friend Email Physician More Information