Cancer Treatment Results  Survival Rates Cancer Treatments / Therapy Results
Cancer
 

Click here to go back to your search results.

Bladder Cancer treatment details. Biologic therapy. University of Michigan Comprehensive Cancer Center, Ann Arbor, MI, United States



Survival: 10.5 months
   
Toxicity Grade: 5
   
Treatments: Biologic therapy
   
Drugs:
Country: United States
   
City/State/Province: Ann Arbor, MI
   
Hospital: University of Michigan Comprehensive Cancer Center
   
Journal: Link
   
Date: 11/2013

Description:
Patients:
This phase 2 study involved 26 previously treated advanced urothelial carcinoma patients. The median patient age was 69 years and 77% were male.

Treatment:
Patients were treated with the biologic therapy agent called sunitinib, a tyrosine kinase inhibitor of the VEGF protein that interferes with tumor growth.

Toxicities:
There was one reported death due to urinary tract infection and subsequent septic shock, although this was considered to be not related to treatment. Grade 4 thrombocytopenia and fatigue were also reported.

Results:
The median overall survival was 10.5 months.

Support:
This study was supported by Pfizer, makers of sunitinib.

Correspondence: Dr. Maha Hussain; email: mahahuss@umich.edu

E-mail to a Friend Email Physician More Information