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Colon Cancer treatment details. Biologic therapy. Institut Gustave Roussy, Villejuif, France



Survival: 9.3 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
   
Drugs:
Country: France
   
City/State/Province: Villejuif
   
Hospital: Institut Gustave Roussy
   
Journal: Link
   
Date: 2/2014

Description:
Patients:
This study involved 25 EGFR-positive, KRAS-mutant, advanced colorectal cancer patients who had been previously treated. The median patient age was 63 years and 56% were male.

Treatment:
Patients were treated with the biologic therapy agent called imgatuzumab, which is a monoclonal antibody against the EGFR protein that interferes with tumor growth.

Toxicities:
The most severe toxicities were of grade 4 and included grade 3-4 rash, fungal infection, and magnesium deficiency.

Results:
The median overall survival was 9.3 months.

Support:
This study was supported by F. Hoffman La-Roche, Ltd.

Correspondence: Dr. Jean-Charles Soria; email: Jean-Charles.Soria@igr.fr

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