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Colon Cancer treatment details. Biologic therapy. Chemotherapy. David Geffen School of Medicine at University of California at Los Angeles, Los Angeles, CA, United States



Survival: 12.7 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
Chemotherapy
   
Drugs:
Country: United States
   
City/State/Province: Los Angeles, CA
   
Hospital: David Geffen School of Medicine at University of California at Los Angeles
   
Journal: Link
   
Date: 10/2013

Description:
Patients:
This phase 2 study involved 45 elderly and/or frail metastatic colorectal cancer patients. The median patient age was 79 years and 40% were male.

Treatment:
Patients received chemotherapy with capecitabine and biologic therapy with bevacizumab.

Toxicities:
The most severe toxicities were of grade 4 and included grade 3-4 diarrhea, fatigue, and hand-foot syndrome (skin reaction).

Results:
The median overall survival was 12.7 months.

Support:
This study was supported by Genentech.

Correspondence: Dr. Arash Naeim; email: anaeim@mednet.ucla.edu

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