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Lung Cancer treatment details. Biologic therapy. Chemotherapy. Radiation. University of Texas Health Science Center, San Antonio, TX, United States



Survival: 19.4 months
   
Toxicity Grade: 5
   
Treatments: Biologic therapy
Chemotherapy
Radiation
   
Drugs:
Country: United States
   
City/State/Province: San Antonio, TX
   
Hospital: University of Texas Health Science Center
   
Journal: Link
   
Date: 9/2013

Description:
Patients:
This phase 2 study involved 40 non-small-cell lung cancer patients with a median age of 67 years; 65% were male.

Treatment:
Patients were treated with radiation therapy, chemotherapy with paclitaxel and carboplatin, and biologic therapy with cetuximab, an EGFR monocolonal antibody that inhibits tumor growth.

Toxicities:
There was one grade 5 adverse event due to pneumonitis (lung inflammation). Grade 4 infection and pulmonary embolism were also reported.

Results:
The median overall survival was 19.4 months.

Support:
This study was partially supported by Bristol Myers Squibb.

Correspondence: Dr. A. Argiris; email: argiris@uthscsa.edu

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