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Ovarian Cancer treatment details. Biologic therapy. Chemotherapy. Kliniken Essen-Mitte, Essen, Germany



Survival: 11.1 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
Chemotherapy
   
Drugs:
Country: Germany
   
City/State/Province: Essen
   
Hospital: Kliniken Essen-Mitte
   
Journal: Link
   
Date: 12/2013

Description:
Patients:
This phase 2 study involved 15 recurrent ovarian cancer patients who had received prior chemotherapy. The median patient age was 60 years.

Treatment:
Patients received chemotherapy with pegylated liposomal doxorubicin and biologic therapy with vandetanib, a tyrosine kinase inhibitor.

Toxicities:
The most severe toxicities were of grade 4 and included grade 3-4 hand-foot syndrome and mucosal inflammation.

Results:
The median overall survival was 11.1 months.

Support:
This study was supported by AstraZeneca.

Correspondence: Dr. Philipp Harter; email: p.harter@gmx.de

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