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Breast Cancer treatment details. Biologic therapy. Istituto Europeo di Oncologia, Milano, Italy



Survival: 9.4 months
   
Toxicity Grade: 5
   
Treatments: Biologic therapy
   
Drugs:
Country: Italy
   
City/State/Province: Milano
   
Hospital: Istituto Europeo di Oncologia
   
Journal: Link
   
Date: 10/2013

Description:
Patients:
This phase 2 study involved 113 previously treated advanced triple-negative breast cancer patients. The median patient age was 52 years.

Treatment:
Patients were treated with the biologic therapy agent sunitinib, which is a receptor tyrosine kinase inhibitor that interferes with cancer cell growth.

Toxicities:
There were treatment-related deaths due to heart attack, disseminated vascular coagulation (increased blood clotting), and respiratory problems. Grade 4 diarrhea and abdominal pain were also reported.

Results:
The median overall survival was 9.4 months.

Support:
This study was supported by Pfizer Inc.

Correspondence: Dr. Giuseppe Curigliano; email: giuseppe.curigliano@ieo.it

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