Cancer Treatment Results  Survival Rates Cancer Treatments / Therapy Results
Cancer
 

Click here to go back to your search results.

Ovarian Cancer treatment details. Chemotherapy. Imperial College London, London, United Kingdom



Survival: 10.5 months
   
Toxicity Grade: 5
   
Treatments: Chemotherapy
   
Drugs:
Country: United Kingdom
   
City/State/Province: London
   
Hospital: Imperial College London
   
Journal: Link
   
Date: 1/2014

Description:
Patients:
This phase 3 study involved platinum-resistant ovarian cancer patients who were separated into two treatment groups. Group A consisted of 70 women with a median age of 57.5 years, while group B had 72 women with a median age of 59 years.

Treatment:
Patients in group A were given chemotherapy with carboplatin and phenoxodiol.
Patients in group B were given chemotherapy with carboplatin and a placebo.

Toxicities:
In group A, grade 5 adverse events were reported due to disease progression. Grade 3 or higher neutropenia, thrombocytopenia, and vomiting were also reported.

In group B, grade 5 adverse events were reported due to disease progression. Grade 3 or higher neutropenia and thrombocytopenia were also reported.

Results:
The median overall survival rates for groups A and B were 8.8 and 10.5 months, respectively.

Support:
This study was supported by the pharmaceutical company Marshall Edwards, Inc.

Correspondence: Dr. Hani Gabra; email: h.gabra@imperial.ac.uk

E-mail to a Friend Email Physician More Information