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Prostate Cancer treatment details. Biologic therapy. San Camillo and Forlanini Hospitals, Rome, Italy



Survival: 18.2 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
   
Drugs:
Country: Italy
   
City/State/Province: Rome
   
Hospital: San Camillo and Forlanini Hospitals
   
Journal: Link
   
Date: 2/2014

Description:
Patients:
This phase 3 study involved 199 metastatic castration-resistant prostate cancer patients who had received prior platinum-based chemotherapy. All patients were 75 years of age or older.

Treatment:
Patients were treated with the biologic therapy agent called enzalutamide (an androgen receptor inhibitor that interferes with cancer cell growth).

Toxicities:
The most severe toxicities were of grade 4 and included grade 3-4 fatigue, back pain, and anemia.

Results:
The median overall survival was 18.2 months.

Support:
This study was supported by Medivation and Astellas.

Correspondence: Dr. Cora N. Sternberg; email: cstern@mclink.it

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