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Brain Cancer treatment details. Immunotherapy. Northwestern University, Chicago, IL, United States



Survival: 9.8 months
   
Toxicity Grade: 5
   
Treatments: Immunotherapy
   
Drugs:
Country: United States
   
City/State/Province: Chicago, IL
   
Hospital: Northwestern University
   
Journal: Link
   
Date: 1/2014

Description:
Patients:
This phase 2 study involved 41 recurrent glioblastoma patients with a median age of 55 years; 73% were male.

Treatment:
Patients were treated with surgery and immunotherapy with the heat shock protein peptide complex-96 (HSPPC-9) vaccine, which can help the immune system target tumor cells.

Toxicities:
There was one treatment-related death due to thrombocytopenia and subdural hematoma. Grade 3-4 fatigue, leukopenia, and neurological toxicities were also reported.

Results:
The median overall survival was 9.8 months.

Correspondence: Dr. Andrew T. Parsa; email: aparsa@nmff.org

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