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Breast Cancer treatment details. Biologic therapy. The West Clinic, Memphis, TN, United States



Survival: 28.6 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
   
Drugs:
Country: United States
   
City/State/Province: Memphis, TN
   
Hospital: The West Clinic
   
Journal: Link
   
Date: 2/2014

Description:
Patients:
This phase 2 study involved 41 postmenopausal women with hormone receptor-positive, HER2-negative breast cancer. The median patient age was 64.5 years.

Treatment:
Patients were treated with the biologic therapy agent fulvestrant, an estrogen receptor inhibitor that interferes with cancer cell growth, and the chemotherapy agent capecitabine.

Toxicities:
The most severe toxicities were grade 4 hypokalemia (low blood potassium) and pulmonary embolism. Grade 3 hand-foot skin reaction was also reported.

Results:
The median overall survival was 28.65 months.

Support:
This study was supported by Hoffmann-La Roche and AstraZeneca.

Correspondence: Dr. Lee S. Schwartzberg; email: lschwartzberg@westclinic.com

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