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Colon Cancer treatment details. Biologic therapy. Chemotherapy. University Hospital of Besanšon, Besanšon, France

Survival: 24.5 months
Toxicity Grade: 5
Treatments: Biologic therapy
Drugs: Leucovorin
Country: France
City/State/Province: Besanšon
Hospital: University Hospital of Besanšon
Journal: Link
Date: 12/2013

This phase 2 study involved 61 metastatic colorectal cancer patients with a median age of 63.6 years; 57% were male.

Patients were treated with the chemotherapy regimen termed FOLFIRI-3 (irinotecan, leucovorin, and 5-fluorouracil), the biologic therapy agent bevacizumab, and the chemotherapy agent capecitabine.

There was one treatment-related death due to colitis and sepsis. Grade 3-4 diarrhea, neutropenia, and infection were also reported.

The median overall survival was 24.5 months.

Correspondence: Dr. Christophe Borg; email:

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