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Liver Cancer treatment details. Biologic therapy. Radiation. Taipei Medical University Hospital, Taipei, Taiwan Region



Survival: 14.0 months
   
Toxicity Grade: 5
   
Treatments: Biologic therapy
Radiation
   
Drugs:
Country: Taiwan Region
   
City/State/Province: Taipei
   
Hospital: Taipei Medical University Hospital
   
Journal: Link
   
Date: 4/2014

Description:
Patients:
This phase 2 study involved 40 hepatocellular carcinoma patients with a median age of 60 years; 31 were male.

Treatment:
Patients were treated with radiation therapy and the biologic therapy agent sorafenib, a kinase inhibitor that causes cancer cell death.

Toxicities:
There were three treatment-related deaths due to liver failure not deemed to be progressive disease. Grade 3 hand-foot syndrome (skin reaction) and diarrhea were also reported.

Results:
The median overall survival was 14.0 months.

Support:
This study was supported by Bayer Pharmaceuticals.

Correspondence: Dr. Jeng-Fong Chiou; email: sjfchiou@gmail.com

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