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Liver Cancer treatment details. Biologic therapy. Chemotherapy. Chiba University, Chiba, Japan



Survival: 10.5 months
   
Toxicity Grade: 5
   
Treatments: Biologic therapy
Chemotherapy
   
Drugs:
Country: Japan
   
City/State/Province: Chiba
   
Hospital: Chiba University
   
Journal: Link
   
Date: 3/2014

Description:
Patients:
This phase 2 study involved 26 advanced hepatocellular carcinoma patients with an average age of 65.5 years; 88.5% were male.

Treatment:
Patients were treated with the chemotherapy agent S-1 and the biologic agent sorafenib.

Toxicities:
There was one sudden death that may have been related to treatment. Grade 4 low blood sodium and grade 3 liver toxicity and thrombocytopenia were also reported.

Results:
The median overall survival was 10.5 months.

Support:
One of this study’s authors has received funding from Bayer Pharmaceuticals.

Correspondence: Dr. Tetsuhiro Chiba; email: techiba@faculty.chiba-u.jp

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