Cancer Treatment Results  Survival Rates Cancer Treatments / Therapy Results
Cancer
 

Click here to go back to your search results.

Colon Cancer treatment details. Chemotherapy. Immunotherapy. Surgery. Vrije Universiteit Medical Center, Amsterdam, Netherlands



Survival: ?
   
Toxicity Grade: 5
   
Treatments: Chemotherapy
Immunotherapy
Surgery
   
Drugs: Adrucil
Leucovorin
Country: Netherlands
   
City/State/Province: Amsterdam
   
Hospital: Vrije Universiteit Medical Center
   
Journal: Link
   
Date: 4/2002

Description:
Patients: This Phase II study involved 56 patients with colon cancer (stage III).

Treatment: Treatment consisted of surgery followed autologous tumour cell vaccinations and the chemotherapy drugs 5-Fluorouracil (adrucil) and leucovorin.

Toxicity: One patient died of multiple organ failure resulting from the toxicity of 5-FU. In addition, thirty percent of patients experienced grade 3 or 4 toxicity including diarrhea, ileus, mucositis, nausea, vomiting, febrile neutropenia, and deep vein thrombosis.

Results: Overall survival was not discussed.

Support: The study was financially supported by Intracel Corporation. Intracel is a biotechnology company that develops and commercializes cancer vaccines.

Correspondence: AJM van den Eertwegh, MD

E-mail to a Friend Email Physician More Information