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Melanoma treatment details. Immunotherapy. Gustave Roussy Comprehensive Cancer Center, Paris, France



Survival: 15.4 months
   
Toxicity Grade: 4
   
Treatments: Immunotherapy
   
Drugs:
Country: France
   
City/State/Province: Paris
   
Hospital: Gustave Roussy Comprehensive Cancer Center
   
Journal: Link
   
Date: 10/2013

Description:
Patients:
This phase 3 study involved 657 melanoma patients with a median age of 54 years; 54.3% were male.

Treatment:
Patients were given immunotherapy with a vaccine called GM2-KLH/QS-21, which is a GM2 ganglioside vaccine that helps the immune system target tumor cells.

Toxicities:
The most severe toxicities were of grade 4 and included grade 3-4 fatigue, injection site reaction, and muscle pain.

Results:
The median overall survival was 15.48 months.

Support:
This study was supported by Progenics Pharmaceuticals.

Correspondence: Dr. Alexander M.M. Eggermont; email: alexander.eggermont@igr.fr

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