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Colon Cancer treatment details. Chemotherapy. Hospital Barmherzige Schwestern vom heiligen Kreuz, Wels, Austria



Survival: 12.0 months
   
Toxicity Grade: 5
   
Treatments: Chemotherapy
   
Drugs: Adrucil
Camptosar
Leucovorin
Country: Austria
   
City/State/Province: Wels
   
Hospital: Hospital Barmherzige Schwestern vom heiligen Kreuz
   
Journal: Link
   
Date: 7/2004

Description:
Patients: This Phase I/II study involved 63 patients with advanced colorectal cancer.

Treatment: Treatment consisted of three drugs irinotecan (camptosar), folinic acid (leucovorin), and 5-fluorouracil (5-FU, adrucil).

Toxicity: There were three deaths due to septic shock that were possibly or probably treatment-related. Grade 3-4 non-hematological drug-related toxicities included delayed diarrhea, stomatitis, fatigue, and nausea/vomiting.

Results: Median survival was 12.0 months.

Support: No competing interests were declared. Two of the authors have e-mail addresses with pharmaceutical companies one with Aventis and one with Astrazeneca. Irinotecan was supplied by Aventis.

Correspondence: Thomas Kuehr, MD

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