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Lung Cancer treatment details. Biologic therapy. Istituto di Ricovero e Cura a Carattere Scientifico, Milan, Italy



Survival: 7.7 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
   
Drugs:
Country: Italy
   
City/State/Province: Milan
   
Hospital: Istituto di Ricovero e Cura a Carattere Scientifico
   
Journal: Link
   
Date: 6/2014

Description:
Patients:
This phase 3 study involved 134 non-small cell lung cancer patients who had progressed following, or were deemed refractory to, platinum-based chemotherapy. The median patient age was 66 years and 74% were male.

Treatment:
Patients were treated with the biologic erlotinib, a tyrosine kinase inhibitor that interferes with cancer cell growth.

Toxicities:
The most severe toxicities were grade 4 diarrhea and skin reactions.

Results:
The median overall survival was 7.7 months.

Support:
This study was partially supported by Biodesix, a molecular diagnostics company that does not manufacture cancer drugs.

Correspondence: Dr. Vanesa Gregorc; email: vanesa.gregorc@hsr.it

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