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Lung Cancer treatment details. Biologic therapy. Istituto di Ricovero e Cura a Carattere Scientifico, Milan, Italy

Survival: 7.7 months
Toxicity Grade: 4
Treatments: Biologic therapy
Country: Italy
City/State/Province: Milan
Hospital: Istituto di Ricovero e Cura a Carattere Scientifico
Journal: Link
Date: 6/2014

This phase 3 study involved 134 non-small cell lung cancer patients who had progressed following, or were deemed refractory to, platinum-based chemotherapy. The median patient age was 66 years and 74% were male.

Patients were treated with the biologic erlotinib, a tyrosine kinase inhibitor that interferes with cancer cell growth.

The most severe toxicities were grade 4 diarrhea and skin reactions.

The median overall survival was 7.7 months.

This study was partially supported by Biodesix, a molecular diagnostics company that does not manufacture cancer drugs.

Correspondence: Dr. Vanesa Gregorc; email:

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