Cancer Treatment Results  Survival Rates Cancer Treatments / Therapy Results
Cancer
 

Click here to go back to your search results.

Non-Hodgkin's Lymphoma treatment details. Biologic therapy. Johannes Gutenberg-University, Mainz, Germany



Survival: 12.8 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
   
Drugs:
Country: Germany
   
City/State/Province: Mainz
   
Hospital: Johannes Gutenberg-University
   
Journal: Link
   
Date: 8/2009

Description:
Patients:
This phase 3 study involved 54 previously treated, relapsed or refractory mantle cell lymphoma patients. The median patient age was 68 years and 85% were male.

Treatment:
Patients were treated with the biologic therapy agent temsirolimus, an inhibitor of the mTOR kinase that interferes with cancer cell growth.

Toxicities:
The most severe toxicities were of grade 4 and included grade 3-4 thrombocytopenia, anemia, neutropenia, weakness, and infection.

Results:
The median overall survival was 12.8 months.

Support:
This study was supported by Wyeth Pharmaceuticals, makers of the study drug.

Correspondence: Dr. Georg Hess; email: g.hess@3-med.klinik.unimainz.de

E-mail to a Friend Email Physician More Information