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Prostate Cancer treatment details. Chemotherapy. Hormone. University of Ulsan College of Medicine, Seoul, Korea



Survival: 17.6 months
   
Toxicity Grade: 5
   
Treatments: Chemotherapy
Hormone
   
Drugs:
Country: Korea
   
City/State/Province: Seoul
   
Hospital: University of Ulsan College of Medicine
   
Journal: Link
   
Date: 5/2014

Description:
Patients:
This phase 3 study involved 33 castration-resistant prostate cancer patients who had received prior docetaxel-based chemotherapy. The median patient age was 67 years (range: 52-88).

Treatment:
Patients received chemotherapy with gemcitabine and oxaliplatin and the steroid hormone prednisolone.

Toxicities:
There were three treatment-related deaths due to gastrointestinal bleeding (1 patient) and viral pneumonia (2 patients). Grade 4 neutropenia, leucopenia and thrombocytopenia, and grade 3 diarrhea were also reported.

Results:
The median overall survival was 17.6 months.

Support:
Study drugs were donated by Chong Kun Dang Pharmaceutical Co. and Boryung Co.

Correspondence: Dr. J-L Lee; E-mail: jaelyun@amc.seoul.kr

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