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Bladder Cancer treatment details. Chemotherapy. Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy



Survival: 19.5 months
   
Toxicity Grade: 5
   
Treatments: Chemotherapy
   
Drugs: Methotrexate
Country: Italy
   
City/State/Province: Milan
   
Hospital: Fondazione IRCCS Istituto Nazionale dei Tumori
   
Journal: Link
   
Date: 6/2014

Description:
Patients:
This study involved 157 metastatic urothelial cancer patients with a median age of 60 years. No gender information was provided.

Treatment:
Patients were treated with the chemotherapy regimen called MVAC, which consists of methotrexate, vinblastine, doxorubicin, and cisplatin.

Toxicities:
There were two treatment-related deaths due to sepsis (infection). Grade 3-4 neutropenia, thrombocytopenia, and mucosal inflammation were also reported.

Results:
The median overall survival was 19.5 months.

Correspondence: Dr. Andrea Necchi; email: andrea.necchi@istitutotumori.mi.it

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