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Lung Cancer treatment details. Biologic therapy. Chemotherapy. Radiation. Instituto Nacional de Cancerología, Mexico City, Mexico



Survival: 26.9 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
Chemotherapy
Radiation
   
Drugs:
Country: Mexico
   
City/State/Province: Mexico City
   
Hospital: Instituto Nacional de Cancerología
   
Journal: Link
   
Date: 5/2014

Description:
Patients:
This phase 2 study involved 35 locally advanced non-small cell lung cancer patients who had not received prior treatment. The average patient age was 59.9 years and 51.6% were male.

Treatment:
Patients received chemotherapy with cisplatin and vinorelbine, radiation therapy, and nitroglycerin, a biologic therapy agent that inhibits production of proteins that support tumor growth.

Toxicities:
The most severe toxicities were of grade 4 and included grade 3-4 neutropenia, nausea/vomiting, and esophagitis. Grade 2 headache was also reported.

Results:
The median overall survival was 26.9 months.

Correspondence: Dr. Oscar Arrieta; email: ogar@unam.mx

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