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Rectal Cancer treatment details. Chemotherapy. Various, Athens, Greece

Survival: 15.0 months
Toxicity Grade: 5
Treatments: Chemotherapy
Drugs: Adrucil
Country: Greece
City/State/Province: Athens
Hospital: Various
Journal: Link
Date: 1/2003

Patients: This Phase II study involved 55 patients with advanced colorectal carcinoma.

Treatment: Treatment consisted of three chemotherapy drugs irinotecan (camptosar, CPT-11), leucovorin, and 5-fluorouracil (5-FU, adrucil).

Toxicity: There was one toxic death because of diarrhea, neutropenia, bacteremia, and sepsis. Other toxicities included: leucopenia (grade 1-3), neutropenia (grade 1-3), anemia (grade 1-2), thrombocytopenia (grade 3), nausea/vomiting (grade1-2), asthenia (grade 1-3).

Results: The median overall survival was 15.0 months

Correspondence: H.P. Kalofonos

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