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Non-Hodgkin's Lymphoma treatment details. Biologic therapy. Chemotherapy. Hormone. The Royal Marsden NHS Foundation Trust, London, United Kingdom



Survival: 12.6 months
   
Toxicity Grade: 5
   
Treatments: Biologic therapy
Chemotherapy
Hormone
   
Drugs:
Country: United Kingdom
   
City/State/Province: London
   
Hospital: The Royal Marsden NHS Foundation Trust
   
Journal: Link
   
Date: 7/2014

Description:
Patients:
This study involved 45 relapsed diffuse large B-cell lymphoma patients with a median age of 58 years; 64% were male.

Treatment:
Patients received chemotherapy with gemcitabine and cisplatin and the steroid hormone methylprednisolone with or without the biologic therapy agent rituximab.

Toxicities:
There were two treatment-related deaths due to infection and neutropenia with fever. Grade 3-4 anemia, thrombocytopenia, and blood clots were also reported.

Results:
The median overall survival was 12.6 months.

Support:
Some of the authors have received funds from various pharmaceutical companies.

Correspondence: Dr. David Cunningham; email: David.Cunningham@rmh.nhs.uk

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