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Brain Cancer treatment details. Biologic therapy. Chemotherapy. Radiation. University of California, San Francisco, San Francisco, CA, United States



Survival: 19.8 months
   
Toxicity Grade: 5
   
Treatments: Biologic therapy
Chemotherapy
Radiation
   
Drugs:
Country: United States
   
City/State/Province: San Francisco, CA
   
Hospital: University of California, San Francisco
   
Journal: Link
   
Date: 7/2014

Description:
Patients:
This phase 2 study involved 59 glioblastoma patients with a median age of 54 years. No gender information was provided.

Treatment:
Patients received radiation therapy, chemotherapy with temozolomide, and biologic therapy with erlotinib and bevacizumab.

Toxicities:
There was one treatment-related death reported due to infection. Grade 4 lymphopenia, thrombocytopenia, and blood clots were also reported.

Results:
The median overall survival was 19.8 months.

Support:
This study was partially supported by Genentech.

Correspondence: Dr. Jennifer L. Clarke; email: clarkej@neurosurg.ucsf.edu

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