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Breast Cancer treatment details. Biologic therapy. Chemotherapy. Dicle University School of Medicine, Diyarbakir, Turkey



Survival: 19.1 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
Chemotherapy
   
Drugs:
Country: Turkey
   
City/State/Province: Diyarbakir
   
Hospital: Dicle University School of Medicine
   
Journal: Link
   
Date: 11/2014

Description:
Patients:
This study involved 46 previously treated HER2-positive metastatic breast cancer patients who had brain metastasis. The median patient age at the time of diagnosis was 45 years.

Treatment:
Patients received biologic therapy with lapatinib (a tyrosine kinase inhibitor) and chemotherapy with capecitabine.

Toxicities:
The most severe toxicities were of grade 4 and included grade 3-4 hand-foot skin reaction, nausea/vomiting, and diarrhea.

Results:
The median overall survival was 19.1 months.

Correspondence: Dr. Muhammet Ali Kaplan; email: drmalikaplan@hotmail.com

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