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Colon Cancer treatment details. Immunotherapy. Cancer Vaccine Center, Kurume University, Kurume, Japan



Survival: 16.4 months
   
Toxicity Grade: 4
   
Treatments: Immunotherapy
   
Drugs:
Country: Japan
   
City/State/Province: Kurume
   
Hospital: Cancer Vaccine Center, Kurume University
   
Journal: Link
   
Date: 10/2014

Description:
Patients:
This phase 2 study involved 60 previously treated advanced colorectal cancer patients. The median patient age was 60 years and 33 were male.

Treatment:
Patients received immunotherapy with a personalized peptide vaccine (PPV). The vaccine contained markers of the patientsí own cancer cells so that the immune system would be stimulated to attack those cells.

Toxicities:
The most severe toxicities were grade 4 anemia. Grade 3 leucopenia, lymphopenia, and rash were also reported.

Results:
The median overall survival was 16.4 months.

Correspondence: Dr. Tetsuro Sasada; email: tsasada@med.kurume-u.ac.jp

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