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Liver Cancer treatment details. Biologic therapy. Chemotherapy. Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany



Survival: 20.1 months
   
Toxicity Grade: 5
   
Treatments: Biologic therapy
Chemotherapy
   
Drugs:
Country: Germany
   
City/State/Province: Düsseldorf
   
Hospital: Heinrich-Heine-University Düsseldorf
   
Journal: Link
   
Date: 11/2014

Description:
Patients:
This phase 2 study involved 43 untreated hepatocellular carcinoma patients with an average age of 69 years; 86% were male.

Treatment:
Patients received chemotherapy with transarterial chemoembolization of doxorubicin and biologic therapy with sorafenib.

Toxicities:
Treatment-related deaths due to liver failure and multi-organ failure were reported. Grade 4 diarrhea and grade 3 hand-foot skin reaction, fatigue, and nausea were also reported.

Results:
The median overall survival was 20.1 months.

Support:
This study was supported by Bayer HealthCare.

Correspondence: Dr. Andreas Erhardt; email: andreas.erhardt@cellitinnen.de

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