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Rectal Cancer treatment details. Chemotherapy. Hospital La Paz, Madrid, Spain



Survival: 15.6 months
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs: Camptosar
Raltitrexed
Country: Spain
   
City/State/Province: Madrid
   
Hospital: Hospital La Paz
   
Journal: Link
   
Date: 4/2004

Description:
Patients: This Phase II study involved 91 patients with advanced colorectal cancer.

Treatment: The treatment consisted of two chemotherapy drugs irinotecan (CPT-11, camptosar) and raltitrexed.

Toxicity: Grade 3-4 toxicities included: diarrhea, nausea/vomiting, transaminase increase, stomatitis, febrile neutropenia, anemia, and asthenia.

Results: The median overall survival was 15.6 months.

Support: Astra Zeneca was involved in the study. Astra Zeneca markets raltitrexed.

Correspondence: Dr. J. Feliu

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