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Bladder Cancer treatment details. Biologic therapy. Chemotherapy. Royal Bournemouth Hospital, Bournemouth, United Kingdom



Survival: 12.0 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
Chemotherapy
   
Drugs:
Country: United Kingdom
   
City/State/Province: Bournemouth
   
Hospital: Royal Bournemouth Hospital
   
Journal: Link
   
Date: 11/2014

Description:
Patients:
This phase 2 study involved 63 previously untreated advanced urothelial carcinoma patients. The median patient age was 64 years and 89% were male.

Treatment:
Patients received the chemotherapy agents gemcitabine and cisplatin, in addition to biologic therapy with sunitinib.

Toxicities:
The most severe toxicities were grade 4 and included leukopenia, neutropenia, and thrombocytopenia.

Results:
The median overall survival was 12 months.

Support:
Some of this study’s authors have had previous funding and/or working relationships with some pharmaceutical companies (Pfizer and Boehringer Ingelheim/Novartis).

Correspondence: Dr. Angela Casbard; email: casbardac@cardiff.ac.uk

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