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Rectal Cancer treatment details. Chemotherapy. The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States



Survival: ?
   
Toxicity Grade: 4
   
Treatments: Chemotherapy
   
Drugs: Camptosar
Eloxatin
Country: United States
   
City/State/Province: Houston, Texas
   
Hospital: The University of Texas M.D. Anderson Cancer Center
   
Journal: Link
   
Date: 8/2004

Description:
Patients: This Phase I study involved 14 patients with metastatic colorectal cancer.

Treatment: The treatment consisted of two chemotherapy drugs irinotecan (camptosar) and oxaliplatin (eloxatin).

Toxicity: Toxicities included neutropenia (grade 3-4), nausea/vomiting (grade 1-3), diarrhea (grade 1-3), and neurologic toxicity (grade 1-2).

Results: All patients were eventually withdrawn from the study: 9 because of disease progression, 4 because of toxicity, 1 because of dose reductions. Median overall survival was not discussed.

Support: This study was supported in part by Sanofi-Synthelabo, Inc.

Correspondence: Paulo M. Hoff, MD

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