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Brain Cancer treatment details. Biologic therapy. Chemotherapy. Harvard Medical School, Boston, MA, United States



Survival: 4.3 months
   
Toxicity Grade: 4
   
Treatments: Biologic therapy
Chemotherapy
   
Drugs:
Country: United States
   
City/State/Province: Boston, MA
   
Hospital: Harvard Medical School
   
Journal: Link
   
Date: 11/2014

Description:
Patients:
This study involved 42 recurrent glioblastoma patients who were previously treated with bevacizumab. The median patient age was 49 years and 66.7% were male.

Treatment:
Patients received chemotherapy with carmustine or lomustine in combination with the biologic therapy agent bevacizumab.

Toxicities:
The most severe toxicities were of grade 4 and included grade 3-4 thrombocytopenia, neutropenia, and high blood pressure.

Results:
The median overall survival was 4.3 months.

Correspondence: Dr. Eudocia Q. Lee; email: eqlee@partners.org

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