Cancer Treatment Results  Survival Rates Cancer Treatments / Therapy Results
Cancer
 

Click here to go back to your search results.

Breast Cancer treatment details. Biologic therapy. Hematology and Oncology Specialists, New Orleans, LA, United States



Survival: 5.4 months
   
Toxicity Grade: 5
   
Treatments: Biologic therapy
   
Drugs:
Country: United States
   
City/State/Province: New Orleans, LA
   
Hospital: Hematology and Oncology Specialists
   
Journal: Link
   
Date: 2/2015

Description:
Patients:
This phase 2 study involved 34 human epidermal growth factor receptor 2epositive (HER2+) metastatic breast cancer patients who had received prior treatment with trastuzumab. The median patient age was 55 years and all were female.

Treatment:
Patients received biologic therapy with ridaforolimus, an mTOR inhibitor, and trastuzumab, an antibody that inhibits the HER2 receptor.

Toxicities:
There was one treatment-related death due to bowel perforation. Grade 3-4 stomatitis (inflammation of mouth and lips), leucopenia, and neutropenia were also reported.

Results:
The median overall survival was 5.4 months.

Support:
This study was supported by ARIAD Pharmaceuticals, Inc.

Correspondence: Dr. Milton Seiler; email: milton.seiler@touro.com

E-mail to a Friend Email Physician More Information