Cancer Treatment Results  Survival Rates Cancer Treatments / Therapy Results
Cancer
 

Click here to go back to your search results.

Breast Cancer treatment details. Biologic therapy. Chemotherapy. Institut Universitaire de Cancerologie Université Pierre et Marie Curie, Paris, France



Survival: 23.7 months
   
Toxicity Grade: 5
   
Treatments: Biologic therapy
Chemotherapy
   
Drugs:
Country: France
   
City/State/Province: Paris
   
Hospital: Institut Universitaire de Cancerologie Université Pierre et Marie Curie
   
Journal: Link
   
Date: 11/2014

Description:
Patients:
This phase 3 study involved HER2-negative metastatic breast cancer patients who were divided into two separate treatment groups. There were 94 patients in group A with a median age of 54 years, and 91 patients in group B with a median age of 49 years.

Treatment:
Patients in group A received biologic therapy with bevacizumab and chemotherapy with docetaxel.

Patients in group B received biologic therapy with bevacizumab and chemotherapy with docetaxel and capecitabine.

Toxicities:
There was one treatment-related death due to heart failure in group A. Grade 3 gastrointeritis was also reported.

There was one treatment-related death due to kidney failure in group B. Grade 4 heart attack and grade 3 hand-foot skin reaction were also reported.

Results:
The median overall survival for groups A and B was 23.7 and 39.0 months, respectively.

Support:
This study was supported by F Hoffmann-La Roche.

Correspondence: Dr. Joseph Gligorov; email: joseph.gligorov@tnn.aphp.fr

E-mail to a Friend Email Physician More Information