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Mesothelioma Cancer treatment details. University Hospital of Siena, Siena, Italy



Survival: 11.3 months
   
Toxicity Grade: 5
   
Treatments:
   
Drugs:
Country: Italy
   
City/State/Province: Siena
   
Hospital: University Hospital of Siena
   
Journal: Link
   
Date: 4/2015

Description:
Patients:
This phase 2 study involved 29 malignant mesothelioma patients who had received prior chemotherapy. The median patient age was 65 years; no gender information was provided.

Treatment:
Patients received biologic therapy with tremelimumab, a monoclonal antibody that binds to the CTLA-4 protein to direct immune cells to kill cancer cells.

Toxicities:
There was one death on treatment due to infection. Grade 3-4 gastrointestinal adverse events were also reported.

Results:
The median overall survival was 11.3 months.

Correspondence: Dr. Michele Maio; email: mmaiocro@gmail.com

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