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Mesothelioma Cancer treatment details. Memorial Sloan Kettering Cancer Center, New York, NY, United States



Survival: 7.1 months
   
Toxicity Grade: 5
   
Treatments:
   
Drugs:
Country: United States
   
City/State/Province: New York, NY
   
Hospital: Memorial Sloan Kettering Cancer Center
   
Journal: Link
   
Date: 4/2015

Description:
Patients:
This phase 3 study involved 329 previously treated, advanced malignant pleural mesothelioma patients. The median patient age was 64 years and 86% were male.

Treatment:
Patients received chemotherapy with vorinostat.

Toxicities:
Three treatment-related deaths due to kidney failure and pneumonia were reported. Grade 3-4 fatigue, shortness of breath, and diarrhea were also reported.

Results:
The median overall survival was 7.1 months.

Support:
This study was supported by Merck.

Correspondence: Dr. Lee M Krug; email: krugl@mskcc.org

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